Medicine - Veterinary > Civil Veterinary Departments > Indian Civil Veterinary Department memoirs > No. 1 - Report of the research work of the Imperial Bacteriological Laboratory Muktesar, 1908-09
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Hæmorrhagic Septicæmia. 55
|
Subcutaneously. |
Intravenously. |
|
0.500 c.c. |
1.0 c.c. |
|
1.000 c.c. |
2.5 c.c. |
|
5.0 c.c. |
|
|
7.5 c.c. |
|
|
10.0 c.c. |
|
|
12.5 c.c. |
About 21 days after the last injection, the bulls were bled
2500 c. c. from the jugular vein. Twenty-four hours after
they were bled a second time, a similar quantity. A period
of over five months was necessary to prepare this serum.
Frequently deaths occurred after an injection of culture.
The sera preparing bulls appeared not to be immunised
against the disease. As has been observed in the preparation
of other anti-toxic sera, the repeated injections of the
toxic products established in certain animals a condition of
anaphylaxis.
Among one batch of serum preparing bulls five deaths
occurred.
|
Bull (1) died 2 days after the injection of 0.2 c.c. subcut. |
|||
|
„ (2) „ |
„ |
„ |
1 c.c. |
|
„ (3) „ |
„ |
„ |
the first injection, subcut. |
|
„ (4) „ |
„ |
„ |
0.5 c.c. subcut. |
|
„ (5) „ |
„ |
„ |
0.05 c.c. „ |
Testing of Serum A.
In all the following tests 0.1 c.c. of a 48 hours broth
culture of Hæmorrhagic Septicæmia was used. Fresh
cultures from a rabbit or bull dead of the disease were, in
most instances, employed, and as controls two udlls were
inoculated with a similar amount of the virus alone.
TEST I.
Serum and Virus simultaneously.
The dose of serum and the virus were inoculated subcu-
taneously on either side.
|
Hill Bull. |
Serum. |
Virus. |
Result. |
|
c.c. |
c.c. |
||
|
1 |
1 |
0.1 |
Died 48 hours. |
|
2 |
1 |
0.1 |
„ 36 „ |
|
3 |
20 |
0.1 |
„ after 3 days. |
|
4 |
20 |
0.1 |
„ „ 50 hours. |
|
5 |
20 |
0.1 |
„ „ 50 „ |
|
6 |
20 |
0.1 |
Lived, Temp. Reaction 39.2°C. |
|
7 |
20 |
0.1 |
„ „ 39.0°C. |
|
8 |
1 |
0.1 |
„ „ „ 39.0°C. |
|
9 |
1 |
0.1 |
„ „ 30.0°C. |
|
10 |
1 |
0.1 |
„ No reaction. |
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| Permanent URL | https://digital.nls.uk/75511990 |
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| Shelfmark | IP/RA.10 |
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| Description | Covers 1908-1911. Describes work on surra, rinderpest, haemorrhagic septicaemia and anthrax, diseases affecting chiefly horses, camels, cattle and dogs. Colour plates and black and white photographs throughout. |
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| Description | Reports dated 1887-1950 record activities of the Civil Veterinary Department across India. Plus minutes, memoirs and ledgers concerning veterinary officers and their work. |
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| Shelfmark | India Papers |
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| Description | The Veterinary collection consists of 146 volumes dating from 1864 to 1959. Divided into veterinary diseases, colleges and laboratories and Civil Veterinary Departments. Extensive research on trypanosomiasis and rinderpest. Reports show how veterinary medicine controlled disease, maintained livestock and alleviated famine. They explore its effect on military and local communities. |
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| Shelfmark | India Papers |
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| Description | The India Papers collection contains publications of the central (Imperial) Government and many Indian states. Most states came under British rule. Much of the collection dates from between the post-Mutiny re-organisation of the Indian Government and Indian Independence in 1947. Some items published in London by John Murray. |
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| Shelfmark | India Papers |
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