Medicine - Veterinary > Civil Veterinary Departments > Indian Civil Veterinary Department memoirs > No. 1 - Report of the research work of the Imperial Bacteriological Laboratory Muktesar, 1908-09
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54 Hæmorrhagic Septicæmia.
|
No. |
Dose. |
How prepared. |
How injected. |
Result. |
|
6 |
0.8 |
Filtered ... |
Intrav. ... |
Died in 36 hrs. |
|
G. Pig |
1 |
„ ... |
Subcut. ... |
„ 38 „ |
|
Sheep. |
||||
|
1 |
0.5 |
Filtered ... |
Tntrav. ... |
No effect. |
|
2 |
1 |
„ ... |
„ ... |
„ |
|
3 |
5 |
„ ... |
„ |
„ |
|
Cattle. |
||||
|
1 |
5 |
Sterilised by Toluol .. |
Intrav. |
Died in 15 hrs. |
|
2 |
5 |
Filtered ... |
„ ... |
„ 40 „ |
|
3 |
10 |
„ ... |
„ ... |
„ 36 „ |
|
4 |
10 |
„ (3 weeks old) ... |
„ ... |
„ 2 days. |
|
5 |
5 |
Sterilised at 10°0 for |
„ ... |
No effect. |
|
6 |
10 |
„ ... |
„ ... |
„ |
|
7 |
200 |
Filtered . |
Subcut. |
„ |
|
8 |
50 |
„ ... |
„ ... |
„ |
|
9 |
1 c.c. of a solution of 1 gramme Dried |
Intrav ... .... |
Died in 12 hrs. |
|
|
10 |
10 |
Filtered ... |
„ ... |
No effect. |
|
11 |
10 |
„ |
„ |
„ |
IMMUNISATION BY MEANS OF SERUM.
In order to ascertain the possibility of preparing an anti-
serum of high potency and capable of conferring an immunity
of long duration, four methods of hyper-immunising animals
were tested.
(1) By increasing small injections of living cultures, first
given subcutaneously and later on intravenously. Serum A.
(2) By subcutaneous injections of large quantities of
living cultures up to 1000 c.c. Serum B.
(3) By subcutaneous inoculation of a mass of living
bacilli obtained from old cultures by centrifugalising.
Serum C.
(4) By subcutaneous injections of the filtrate (Toxin
alone) from broth cultures 48 hours. Serum D.
METHOD OF PREPARATION OF SERUM A.
Plains bulls, averaging 500 lbs., were injected with 5 c.c.
of an anti-serum subcut. and, 48 hours after, inoculated with
0.025 c.c. of an H.S. culture.
Following this at intervals of 10 days, they receive increas-
ing doses as follows :—
|
Subcutaneously. |
Intravenously. |
|
0.050 c.c. |
0.1 c.c. |
|
0.100 c.c. |
0.2 c.c. |
|
0.200 c.c. |
0.5 c. |
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Images and transcriptions on this page, including medium image downloads, may be used under the Creative Commons Attribution 4.0 International Licence unless otherwise stated. 
| Permanent URL | https://digital.nls.uk/75511987 |
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| Shelfmark | IP/RA.10 |
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| Description | Covers 1908-1911. Describes work on surra, rinderpest, haemorrhagic septicaemia and anthrax, diseases affecting chiefly horses, camels, cattle and dogs. Colour plates and black and white photographs throughout. |
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| Description | Reports dated 1887-1950 record activities of the Civil Veterinary Department across India. Plus minutes, memoirs and ledgers concerning veterinary officers and their work. |
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| Shelfmark | India Papers |
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| Description | The Veterinary collection consists of 146 volumes dating from 1864 to 1959. Divided into veterinary diseases, colleges and laboratories and Civil Veterinary Departments. Extensive research on trypanosomiasis and rinderpest. Reports show how veterinary medicine controlled disease, maintained livestock and alleviated famine. They explore its effect on military and local communities. |
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| Shelfmark | India Papers |
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| Description | The India Papers collection contains publications of the central (Imperial) Government and many Indian states. Most states came under British rule. Much of the collection dates from between the post-Mutiny re-organisation of the Indian Government and Indian Independence in 1947. Some items published in London by John Murray. |
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| Shelfmark | India Papers |
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