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     Again, at the end of the sixth week and a fortnight after the temperature had
come to normal the serum tested with the same two emulsions gave the follow-
ing reaction:—

Dilution of serum. Stock. Multan I.
1—80 Complete sedimenta-tion. Complete sedimenta-tion.
1—160 Complete ,, Complete ,,
1—320 Trace of ,, Well marked ,,
1—640 No ,, Trace of ,,
1—1,280 No ,, No ,,

     Blood was withdrawn from the spleen at the end of the second week.
M. Melitensis was isolated in pure culture (Ferozepore I).

     Case XI.—Mr. M.; aged 32, Ferozepore. Patient had been ten years
resident in India before the present illness. He came under observation for
the first time on 18th May 1905. Before this date he had suffered from fever
for a week. For temperature vide chart XI. During the short time of which
there is no temperature record the patient was removed from Ferozepore to
the Murree Hills. He states, however, that during this period his temperature
was above normal. The fever continued for several weeks after his arrival in
the hills and at the time of writing is still present. Constipation was trouble-
some throughout. Further, he complained a good deal of joint pains, first in the
left shoulder, next in the right shoulder and then more generally in several
of the other joints. Latterly severe pain was complained of in the right hip
and back, There was no orchitis.

     The serum reaction with M. Melitensis, first examined towards the begin-
ning of the illness, namely on the tenth day, was as follows:—

Dilution of serum. Stock. Multan I.
1—80 Complete sedimenta-tion. Complete sedimenta-tion.
1—160 Complete ,, Complete ,,
1—320 Complete ,, Complete ,,
1—640 Well marked ,, Complete ,,
1—1,280 No ,, No ,,

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