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dog's cells without the addition of extracellular complement, vary considerably
in the degree of this action. Thus, cobra venom and daboia venom even in
small amount have a complete hæmolysing effect; the venoms of Bungarus
cæruleus and Echis carinata have a complete action only when used in large
quantity, while the poison of Hoplocephalus curtus has only a slight effect even
when present in comparatively large amount. Group 2, namely, those venoms
which have no hæmolytic action on dog's washed cells, consists of the poisons
of Naja bungarus, Bungarus fasciatus, Enhydrina valakadien, Trimeresurus
gramineus and Crotalus adamanteus.

     Turning now to table II, in which are set forth the results obtained with the
same quantities of the same poisons as in the experiments recorded in table I but
with the addition of serum complement, the homologous serum being used for
this purpose, we find that all venoms have now a marked hæmolytic action and
that with the exception of the venom of Enhydrina valakadien the quantitative

Table II.

Amount of
venom in
milli-
grammes.
DOG'S WASHED CELLS: 1 C.C. OF 5 PER CENT. SUSPENSION. DOG'S SERUM: 0.5 C.C. OF 2-FOLD DILUTION.
N. T. V. N. B. V. B. C. V. B. F. V. H. C. V. E. V. V. D. R. V. E. C. V. T. G. V. C. A. V.
5 C. H. C. H. C. H. C. H. C. H. Nearly
C. H.
C. H. C. H. C. H. C. H.
1 C. H. C. H. C. H. C. H. C. H. Nearly
C. H.
C. H. C. H. C. H. C. H.
0.5 C. H. C. H. C. H. C. H. C. H. Nearly
C. H.
C. H. C. H. C. H. C. H.
0.1 C. H. C. H. C. H. C. H. C. H. Nearly
C. H.
C. H. C. H. C. H. C. H.
0.05 C. H. C. H. Nearly
C. H.
C. H. C. H. Well
marked.
C. H. C. H. C. H. C. H.
0.01 C. H. C. H. Nearly
C. H.
C. H. Nearly
C. H.
Trace. C. H. Marked. C. H. C. H.
0.005 Nearly
C. H.
Marked. Marked Nearly
C. H.
Nearly
C. H.
Trace. C. H. Mere
trace.
C. H. C. H.
0.001 Marked. Mere
trace.
Trace. No H. Slight No H. Nearly
C. H.
No H. Slight. Nearly
C. H.
0.0005 Slight. No H. No H. No H. Trace. No H. Slight. No H. Trace. Mere trace.

C.H.=Conplete hæmolysis.

differences to be made out between the individual poisons are not great.

      It is also to be noted that smaller amounts of both cobra and daboia poisons

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