Medicine - Institutions > Army health reports and medical documents > Scientific memoirs by medical officers of the Army of India > Part XI, 1898 > 1 - Physiological action of cobra-venom
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Medical officers of the Army of India.
TABLE VIII.
Phenomena presented by specimens of fowls' blood treated with boiled Cobra-venom.
| No. of- experi- ment. |
Treatment of solution of venom. | Nature of speci- men. |
Coagulation. | Colour. | Solution of bodies of erythrocytes. |
Reduction in respiratory property of hæmoglobin. |
Putrefaction. |
| I | Just brought to boil. |
Blood, 9 c c.; venom, 0.00075 gramme; water I c. c. |
Firm, 4 minutes; clot highly contracted in 3 hours. |
Substance of clot still bright plum-coloured, 3 hours. |
Greater number of ery- throcytes intact, 3 hours; many still undissolved, 24 hours. |
Absent, 24 hours; slight, 48-72 hours; hardly per- ceptible, 96 hours. |
|
| II | Just brought to boil. |
Blood, 9 c. c.; venom, 0.002 gramme; water I c. c. |
Firm, 4 minutes; pale red serum present, I hour; large quan- tity deep red serum, 24 hours. |
Substance of clot very deep plum-coloured, 3 hours; black, 24 hours. |
Greater number of ery- throcytes dissolved, 3 hours; solution complete, 24 hours. |
Perceptible, 24 hours. | |
| III | Just brought to boil. |
Blood, 9 c. c.; venom, 0.01 gramme; water, 1 c.c. |
Firm, 3 minutes; no contraction. |
Black, 1 hour | Complete, a hour | Considerable, 24 hours; very great, 48-72 hours; almost absent, 96 hours; absent, 120 hours. |
Faint odour, 96 hours. |
| IV | Just brought to boil. |
Blood, 9 c. c.; venom, 0.01 gramme; water 1 c. c. |
Firm, 5 minutes; a considerable amount of deep red serum, 24 hours. |
Black, 40 minutes | Complete, 40 minutes | Conspicuous, 24 hours; absent, 48 hours. |
Odour present, 48 hours. |
| V | Just brought to boil. |
Blood, 9 c. c.; venom, 0.01 gramme; water, I c. c. |
Firm, 5 minutes; no contraction. |
Black, 30 minutes | Complete, 30 minutes | Perceptible, 24 hours; absent, 48 hours. |
Slight odour pre- sent, 48 hours. |
| VI | Just brought to boil. |
Blood, 9 c, c.; venom, 0.01 gramme; water, 1 c. c. |
Immediate; no con- traction. |
Black, 2 hours 20 minu- tes. |
Distinct, 24 hours; very great, 48-72-96 hours; thereafter progressive diminution; absent, 168 hours. |
Slight odour, 168 hours. |
|
| VII | Brought to boil and then steamed for 3 hours. |
Blood, 9 c. c.; venom, 0.01 gramme; water, 1 c. c. |
Firm, 6 minutes; no contraction. |
Substance of clot deep plum-coloured, 3 hours 20 minutes; black, 24 hours. |
Erythrocytes deformed and partially bleached, 3 hours 20 minutes; solu- tion complete, 24 hours. |
Distinct, 24 hours. | |
| VIII | Brought to boil three times and then steamed for 6 hours. |
Blood, 9 c. c.; venom, 0.01 gramme; water, 1 c. c. |
Firm, 4 minutes; con- siderable contraction, 2½ hours; consider- able quantity of pale red serum, 24 hours. |
Substance of clot plum- coloured, 2½ hours; black, 24 hours. |
Hardly any solution and no deformation, 2½ hours; al most complete, 24 hours. |
Barely perceptible, 24 hours; very considerable, 48 hours; very great, 72 hours; absent, 96 hours. |
Slight odour, 96 hours. |
| IX | Boiled for 6½ hours. |
Blood, 9 c. c.; venom, 0.01 gramme; water, 1 c. c. |
Firm, 3 minutes; red- dish serum exuding, 1 hour; large amount of deep red serum, 24 hours. |
Substance a clot deep plum-coloured, 24 hours. |
Very little solution, 24 hours; complete solu- tion, 48 hours.* |
Absent, 24 hours; barely perceptible, 48-72 hours; absent, 96 hours. |
Odour present, 96 hours. |
*The, rate at which solution took place in this case was not greater than that sometimes present in cases in which a corresponding ratio of water alone is present.
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