24                                 Surra.

In four cases Nos. 260, 245, 283 and 285 the treatment
has been successful.

In 263 the treatment failed and trypanosomes reappeared
in the blood.

Ponies 282, 280 (and four others not here recorded) died
under the treatment.

In the case of Pony 263 atoxyl and orpiment treatment
had no good result. Following this, atoxyl, orpiment and
tartar emetic were administered for 15 days and apparently
effected a cure.

Pony 287 was treated with tartar emetic and sodium
arsenite. After the treatment ceased, the trypanosomes again
appeared in the blood. A combination of atoxyl, orpiment and
sodium arsenite was then tried with success.

Pony 288 was treated with sodium arsenite (drench),
tartar emetic (intrav.) and orpiment (ball). This treatment
failed. When the pony was in an advanced stage of the
disease, the combination of sodium arsenite, atoxyl and
orpiment was administered with a successful result.

The same combinaton, atoxyl, orpiment and sodium
arsenite was administered to Pony 292. One injection of
atoxyl, 2 doses of sodium arsenite and 2 doses of orpiment
were given with a successful result.

In cases Nos. 258 and 265 the atoxyl and orpiment were
administered at the same time. The result was not good.
Following this the alternate method was tried but did not
succeed.

Pony 289 was treated with tartar emetic and orpiment.
He died under treatment.

The results of these experiments show that Surra in rab-
bits and guinea-pigs can be cured by a few doses of atoxyl
and orpiment administered according to the method of Lave-
ran and Thiroux even when the disease is well established
and that the treatment is accompanied with little risk.

That in ponies and horses the same treatment can effect
a cure even in advanced cases (Horse 245), but that it does
not succeed in all cases ; and that all animals cannot tolerate
the drugs. It is probable that further experiments may