36      THE INDIAN JOURNAL OF VETERINARY SCIENCE AND ANIMAL HUSBANDRY [ I, I

to say in reply that John Doe recommended so much ferrous sulphate given thus
and so, and Richard Roe recommended so much tartar emetic given this way or
that, for the removal of this or that parasite from such and such a host, and this
was obviously an unsatisfactory answer. To remedy this situation, the late Dr. B.
H. Ransom, a capable and sound scientist, who was then Chief of the Zoological
Division, inaugurated a project on anthelmintic medication. The results obtained
from that project have paid large returns to agriculture and the veterinary and
medical profession, and have done much to stimulate interest in the subject of
anthelmintics. The present writer was detailed in charge of this work, and was
associated from time to time with Foster, Shillinger, Gram and Wigdor. The
writer's administrative work of the past five years has prohibited any considerable
active participation in these investigations, and the actual investigations at present
are being carried out by Dr. W. H. Wright. This paper, therefore, represents the
observations of an old campaigner no longer on active duty, and might appropriately
be tinged with regret at the necessity for confinement to paper work at a time when
the subject of anthelmintics is entering the stage of basic scientific investigation,
and when there is active warfare on all fronts and " lovely fighting along the
whole line ".

      Characteristically, the scientist who is no longer a youngster actively engaged
in research turns to philosophic speculations, the summarising of knowledge, the
correlation of other men's findings, and the formulation of principles. Conforming
to this habit, the writer proposes to discuss certain principles of anthelmintic
medication. This subject he has discussed in several previous papers, but our
principles may be regarded as tentative to the extent that they are subject to
modification in the light of additional knowledge, and they need occasional revision.
They may be taken as representing ideas which have grown out of an experience
that is extensive by comparison with that of other workers in this field, and out of
a rapidly increasing fund of available knowledge, and they are of value as back-
ground in the consideration of the individual cases the veterinarian will have to
consider in practice or research.

                        PRINCIPLES OF ANTHELMINTIC MEDICATION.
      I. Factors in Anthelmintic Medication. Elsewhere the writer has noted that
the important factors in anthelmintic medication may be stated alliteratively as :
(1) The practitioner ; (2) the patient ; (3) the parasite ; (4) the parasiticide ;
(5) the purgative ; and (6) prophylaxis. These may be discussed very briefly as
follows :—

      (1) The Practitioner, i.e., the veterinarian or physician, must know all the
            other factors not superficially, but well, and must be a person of sound