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   Films of splenic blood showed distinct agglutination and many spherocytes. Some de-
colourised included red cells present. Macrophages contain engulfed small mononuclear cells.

   Hœmolysis experiments:—

½ c.c. washed B.W.F. corpuscles emulsions 150 c.m. normal serum. Rapid hæmolysis.
½ c.c. washed B.W.F. corpuscles mulsions 150 c.m. normal serum+50 c.m. No hæmolysis.
  B.W.F. serum at 37 for 15 min. Aggultination.
Washed B.W.F. corpuscles Allowed to stand in .9% salt. No hæmolysis.

         11th May 1908.—Small quantity passed free from hæmoglobin. Hæmoglobinæmia no
longer to be detected. Serum bright yellow but free from hæmoglobin.

Case XXV.—Nagasuri. May 1908.

   Bengali Babu, Age 30.

           Native country.—Murshidabad.

          Length of residence in Duars.5 years.

         History.—At his home scarcely had one attack of fever in the year; in the Duars
had two or three attacks every month. Has been one year at Nagasuri living in
the midst of coolie lines.

         29th May 1908.—About midnight he had an attack of fever but with a more severe
 sensation of cold and shivering than usual. In the morning noticed that
 his urine was red.

         30th and 31st May and 1st June 1908.—Passed hæmoglobinous urine. Had severe
 epigastric pain and much vomiting, especially on the 31st. Jaundice was first
 noticed on the 30th and was very marked on the 31st.

         2nd June 1908.—Urine dark in the morning but subsequently cleared. Blood film taken
 by Dr. McCutcheon.

         Seen by us on the 3rd.—Hæmoglobinuria over. Spleen enlarged. Yellow colouration of
conjunctivæ present. Marked tenderness over the liver, less so over the spleen.
Serum yellow. No hæmoglobinæmia. Clot dissolved to some extent overnight
though it did not do so in a control blood.

  Hœmolysis experiments—

½ c.c. washed B.W.F. emulsions + 150 c.m. normal serum, S. R. C. No hæmolysis.
  No agglutination.
Washed B.W.F. corpuscles. + Undiluted normal serum S. R. C. No hæmolysis.
  No agglutination.

Case XXVI.—Indong. July 1908.

         Bengali Babu. Age 25.

           Native country.—Dacca.

           Length of Residence in Duars.—3 years.

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