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pathology of plague in experimental animals in addition to routine sections
of pathological tissues for histological examination.

V. SNAKE VENOM.

     The Institute maintains a large number of poisonous snakes from which
venom is collected for the manufacture of anti-venomous sera and the
process of venom extraction is counted as one of the principal attractions
to the visitors. At present the animals from which venom is extracted
are Cobras and Russell's Vipers, but it is hoped that in the near future
other varieties of poisonous snakes will also be tackled and attempts made
for the production of curative sera against their bite.

     The Institute maintains a large library with 150 current monthly and
weekly journals and a collection of recent scientific publications and books
to afford suitable assistance to the workers. Facilities have been afforded
to private individuals for conducting research.

(v) PASTEUR INSTITUTE OF INDIA, KASAULI.

     The Pasteur Institute of India, Kasauli, was founded in 1893 mostly
with the aid of public subscriptions and incorporated as a charitable concern
in 1901. The principal objects of the Institute were:—

          1. The treatment of persons suffering from injuries inflicted by rabid
          animals.

          2. The study, diagnosis, practice and teaching of bacteriology in all
          its branches, especially with reference to the diseases of men,
          animals and plants.

          3. The investigation of tropical diseases and the practical application
          of bacteriological methods to the prevention and cure of disease.

     2. Antirabic treatment was begun on the 9th August 1900 by Major
D. Semple, R.A.M.C. (later Sir David Semple) in a small building called
Manor House which enlarged again and again is the building still occupied
by the Institute. During the first year of its existence the Institute
treated 321 patients. The popularity of the Institute is evident from the
fact that 36 years later in 1936, 18,620 patients received the benefit of
treatment with vaccine manufactured in this Institute. This Institute
besides preparing antirabic vaccine also originally manufactured antivenene,
anti-tetanic and anti-diphtheritic serum. In 1906 the latter part of its
activities was transferred to the Central Research Institute, Kasauli.

     3. The success of this Institute not only led to the opening of the
Central Research Institute but also of other Pasteur Institutes in India at
Coonoor, Shillong, Bombay, Rangoon, Calcutta and Patna.

     4. Researches on rabies mainly with a view to produce a more efficient
vaccine was one of the main functions of this Institute since its inception.
Generous contributions towards this object were received from the Indian
Research Fund Association from 1926 onwards. These researches have
now made it possible to decentralize the treatment. The Institute has
at present more than 140 centres in the Punjab, United Provinces, Delhi
Province, North-West Frontier Province and Indian States where anti-
rabic treatment is administered. Much time has therefore been gained in

Contributed by Dr. R. O. A. Smith, I.M.D.